Changes in Nucleotide Pools during Sporulation of Streptomyces griseus in Submerged Culture
نویسندگان
چکیده
منابع مشابه
Sporulation of Streptomyces griseus in submerged culture.
A wild-type strain of Streptomyces griseus forms spores both on solid media (aerial spores) and in liquid culture (submerged spores). Both spore types are highly resistant to sonication, but only aerial spores are resistant to lysozyme digestion. Electron micrographs suggest that lysozyme sensitivity may result from the thinner walls of the submerged spores. Studies of the life cycle indicate t...
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We used fluorescein-tagged beta-lactam antibiotics to visualize penicillin-binding proteins (PBPs) in sporulating cultures of Streptomyces griseus. Six PBPs were identified in membranes prepared from growing and sporulating cultures. The binding activity of an 85-kDa PBP increased fourfold by 10 to 12 h of sporulation, at which time the sporulation septa were formed. Cefoxitin inhibited the int...
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Leitzmann, Claus (University of Minnesota, Minneapolis), and Robert W. Bernlohr. Changes in the nucleotide pool of Bacillus licheniformis during sporulation. J. Bacteriol. 89:1506-1510. 1965.-An analysis of the amount of acid-soluble nucleotides in Bacillus licheniformis cells showed a 75% increase during presporulation over that in log-phase cells. Cultures in which presporulation was inhibite...
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The production of the antifungal agent cycloheximide by Streptomyces griseus is typical of many antibiotic fermentations. In the initial stage of the fermentation, cell growth is extensive, while little antibiotic is produced. After roughly 24 hours, the biomass concentration remains relatively constant and accumulation of product in the fermentation broth begins. It has been shown that product...
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The aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. Among the actinomycetes screened, Streptomyces griseus NCIM 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in S. griseus NCIM 2623...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1987
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-133-10-2787